Howard Krein is an American otolaryngologist, plastic surgeon, and business executive, widely recognized as the former son-in-law of U.S. President Joe Biden. Born in 1966 in Cherry Hill, New Jersey, he is 59 years old as of 2025.
He works as a professor at Thomas Jefferson University, co-directs the Herbert Kean Center for Facial Aesthetics, and serves as the Chief Medical Officer at StartUp Health. In August 2025, his wife Ashley Biden filed for divorce after 13 years of marriage, as reported by The Philadelphia Inquirer. Krein has also advised Joe Biden’s 2020 presidential campaign on COVID-19 and served on the Biden Cancer Initiative board from 2017 to 2019.
Howard Krein Wiki/Bio
| Full Name | Howard David Krein |
| Date of Birth | 1966 |
| Age | 59 years (as of 2025) |
| Profession | Otolaryngologist, Plastic Surgeon, Business Executive |
| Hometown | Cherry Hill, New Jersey, USA |
| Current Residence | Philadelphia, Pennsylvania, USA |
| Nationality | American |
Physical Details
| Height | 5’10” (1.78 m) |
| Weight | 72 kg (159 lbs, approx.) |
| Eye Color | Brown |
| Hair Color | Brown |
Early Life
Howard Krein was born in Cherry Hill, New Jersey, in 1966, and raised in a Jewish family. His father, Stanley Krein, worked as an insurance executive and former Aetna marketing director, while his mother, Brenda Ferne “Bunny” Lipner Krein, was a physician assistant in cardiology at Cooper University Hospital.
He grew up with two siblings — Steven and Bari. As a teenager, Krein was active in sports and community service. He competed in CowTown, a weekly rodeo in Pilesgrove, New Jersey, and even volunteered as a firefighter at age 16. In interviews, he has said that growing up in New Jersey taught him resilience and shaped his character. His early love for horses and interest in medicine influenced his later career choice.
Education
Howard Krein completed his B.S. in Biology and M.S. in Neuroscience from Rutgers University. He went on to earn a Ph.D. in Cell and Developmental Biology from the University of Medicine and Dentistry of New Jersey’s Robert Wood Johnson Medical School in 1996, followed by an M.D. from Thomas Jefferson University in 2000.
He later completed a fellowship in facial plastic and reconstructive surgery at the Medical College of Virginia, further specializing in complex facial procedures.
Family
Howard Krein’s parents are Stanley Krein and Brenda Ferne “Bunny” Lipner Krein. He has two siblings: Steven Krein, who is the CEO of StartUp Health, and his sister, Bari.
He married Ashley Biden, the daughter of President Joe Biden, in 2012 after being introduced by Beau Biden in 2010. The couple did not have children. In August 2025, after 13 years of marriage, Ashley filed for divorce.
Career Highlights
| Year | Achievement |
| 2007 | Became assistant professor at Thomas Jefferson University |
| 2011 | Appointed Chief Medical Officer at StartUp Health |
| 2017–2019 | Served on Biden Cancer Initiative board |
| 2020 | Advised Joe Biden’s presidential campaign on COVID-19 |
| 2025 | Continued as co-director of Herbert Kean Center for Facial Aesthetics |
Career
Howard Krein is a board-certified otolaryngologist and plastic surgeon, specializing in facial and reconstructive surgery. He has been part of Thomas Jefferson University since 2007, where he teaches and co-directs the Herbert Kean Center for Facial Aesthetics.
Apart from his academic and surgical work, Krein is committed to charitable medical services. He volunteers for Faces of Honor, offering reconstructive surgeries to veterans and victims of domestic violence, and has performed operations for children with facial deformities in Belize.
In 2011, he joined StartUp Health as its Chief Medical Officer, helping develop and support healthcare technology companies. His political involvement includes serving on the Biden Cancer Initiative board from 2017 to 2019 and advising Joe Biden’s 2020 presidential campaign on COVID-19 strategies.
Net Worth
| Estimated Net Worth (2025) | $1–$5 million |
| Income Sources | Medical practice, teaching, StartUp Health |
Howard Krein’s net worth is estimated between $1 and $5 million in 2025. His earnings come from his medical practice, university teaching, and his executive role at StartUp Health.
Controversies
- Conflict of Interest Concerns (2020): Krein faced scrutiny for advising Joe Biden’s 2020 campaign on COVID-19 while holding an executive role at StartUp Health, which invested in pandemic-related startups. He clarified that he had no formal campaign position.
- Divorce Filing (2025): Ashley Biden’s divorce filing in August 2025 drew media attention, especially after her social media posts hinted at a fresh chapter in her life. (Source)
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